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Side effect of statins11/24/2023 ![]() ![]() An ~80 mg/dL (2 mmol/L) reduction over five years with low-cost statin therapy appears to prevent a major vascular event in about 500 out of 10,000 patients who have not yet had a vascular event (primary prevention) and 1,000 out of 10,000 patients who already have ASCVD (secondary prevention). The Cholesterol Treatment Trialists' (CTT) meta-analysis using 27 large-scale trials demonstrated that each ~40 mg/dL (1 mmol/L) reduction in LDL-C with statin therapy decreases risk of major vascular events by ~25% each year after the first year there was a more modest 10-12% reduction in the first year. Robust data show that reducing LDL-C through statin therapy leads to a reduction of ASCVD risk. Patients with high cholesterol develop plaque in their blood vessels, which can limit blood flow and lead to ASCVD events. With the decline of smoking, LDL-C control has become an even more important way to decrease the risk for ASCVD events (heart attacks and strokes). Since 1900, ASCVD has been the leading cause of death every year in the US (except for 1918, the year of the influenza pandemic). Since lovastatin was first approved in 1987 in the US, statins have become the leading pharmacologic treatment for high LDL-C and non-HDL-C. Statins are a class of drug that inhibit one of the first steps in cholesterol synthesis, in turn upregulating LDL receptors and lowering LDL-C generally by 25-50%. Vitamin D supplementation does not seem to reduce the risk of statin-related muscle pain, but there is preliminary evidence that it may reduce the intensity of such pain in people with low vitamin D blood levels.įish oil may also offer benefits to certain people on statin drugs.įor more details about these interactions, use the links above, which take you to articles on ConsumerLab with extensive information about each supplement.High low-density lipoprotein cholesterol (LDL-C) is one of the most common modifiable risk factors for atherosclerotic cardiovascular disease (ASCVD), affecting 78 million US adults (37% of the American adult population) in 2011-2012 according to the Centers for Disease Control and Prevention. In general, CoQ10 supplementation does not appear to reduce statin-related muscle pain, although there is evidence it may help people considered statin-intolerant due to muscle-related side effects when combined with a reduction in statin dose. To play it safe, it may be best to take statins at least a couple of hours before consuming a green tea supplement or beverage. (Note: Another form of this gene is known to increase the activity of simvastatin as well as atorvastatin).Īlthough green tea can help lower cholesterol, it can also decrease absorption of some, but not all, statin drugs. Soy isoflavones were found to reduce the bioavailability of simvastatin by an average of 48% in people carrying a common form of the SLCO1B1 521 gene. However, some other statins do not seem to be affected by grapefruit juice, including pravastatin (Pravachol), fluvastatin (Lescol) and rosuvastatin (Crestor). Since the effects of grapefruit juice may last as long as 3 days, it should be avoided if you are taking atorvastatin (Lipitor), lovastatin (Mevacor, Altoprev) or simvastatin (Zocor). Some fruit juices can also be a problem, particularly grapefruit juice, which impairs the body's normal breakdown of certain statins, allowing them to build up to potentially excessive levels in the blood. Nevertheless, some physicians believe taking niacin in addition to statin medication may be helpful for certain people however do not try this combination without consulting your physician. While high doses of niacin may help to lower cholesterol, studies show that if you already take a statin drug, adding high-dose niacin does not appear to provide additional benefit and may carry serious risks. Red yeast rice, which contains a naturally occurring statin, should not be combined with prescription statin drugs without medical supervision.īerberine should be avoided or used with caution when taking certain statin drugs, such as atorvastatin (Lipitor), lovastatin (Mevacor) and rosuvastatin (Crestor). Certain forms of magnesium may also decrease blood levels of statin drugs - particularly Crestor. John's wort and possibly quercetin, may decrease blood levels of some statin drugs, and when taken with atorvastatin, may actually result in increased cholesterol levels. Atorvastatin (Lipitor), rosuvastatin (Crestor), and other cholesterol-lowering statin drugs can be affected by taking supplements and can affect your ability to absorb certain vitamins and minerals. ![]()
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Venture capital fund model11/24/2023 ![]() ![]() ![]() Portfolio construction is the process of creating your portfolio strategy, check sizes, follow on reserves, and expectations around valuations, ownership, and dilution over time. Create a Portfolio Model By Detailing your Investment Strategy If you then layer on a fees estimate, you’ll be able to forecast capital calls and net out the proceeds and distributions. This means when and how much you’re putting into companies at the first check, and potential follow-ons. Once you have this framework, you should estimate how you’ll deploy capital. This process will take your overall budget into an annual or quarterly budget of cash flows. Then, to fully understand and calculate performance metrics, build a forecast of proceeds from those investments and the resulting distributions from the fund to investors.Add your forecast of expenses to your forecast of investments to create a capital call schedule.Optionally, create a forecast of follow-ons based on your initial investments, follow-on reserve strategy and expected timing between rounds. Build a forecast of new investments over your new investment timeframe.Create a budget for your expected management fees and fund expenses over time.Once you have an overall budget, you should estimate how you’ll deploy capital. A cash flow forecast provides the foundation for that analysis. It’s imperative that you understand the long commitment you’re making into this fund, and how/when you’ll make investment decisions. Not only does it give you a basic understanding of your business and the size of investments you can make from your fund, but a well-designed forecast shows prospective LPs that you know what you’re doing. Once you have this framework in place, you can apply an assumption of gross return multiple on your invested capital to estimate returns.īuilding this model may seem simplistic, but it’s essential for closing your first round of capital. At the same time, factor in assumptions for management fees and carry that most closely relate to your situation. Start with a simple budget including total capital, expenses, investments, proceeds and distributions. There are also some similarities and basic differences that we can leverage to get a running start. Even quantitatively-minded first-time GPs can find modeling a challenge because venture capital models are often quite different from the models you may be familiar with. ![]()
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Markets for factors of production definition11/24/2023 ![]() Moreover, the psychological rewards provided by the job itself are important factor payments. Common examples are employer contributions for health insurance, retirement programs, and other fringe benefits. While wages are typically monetary payments, and result in paychecks, they invariably involve nonmonetary components, too. Wage: This is a payment to the owner of labor in exchange for the productive service of labor.Such factor payments are what entice owners to allocate their resources for productive use. ![]() The factor payment of labor is wage, for capital is interest, for land is rent, and for entrepreneurship is profit. The specific factor payment depends on the specific factor exchanged. The general term for the monetary payments is factor payments. This resource takes the risk of organizing production BEFORE anything is produced and with no guarantee that production will be successful.įactor PaymentsComparable to most markets, factor markets exchange a commodity for a monetary payment or price. A key component of entrepreneurship is risk. Without someone to organize production, the other three factors do NOT produce. Entrepreneurship is the factor that organizes the other three.
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Shadowrun returns editor using all mods11/24/2023 ![]() ![]() ![]() There is also a pinned threat about the best UGCs, it’s a year old, so if anyone feels like making. Some mods might only be available in the Steam Workshop, if you have the games on another platform, you can use Steam Workshop Downloader. Beware of conflicting file names as replacing files may break your game. The mods on Nexus work for everyone: Shadowrun Returns. ![]() Notice that no files need to be overwritten in the game folder with this method. Since all HBS campaigns and most UGC uses the seattle pack as a dependency, either way will essentialy get you the same results (unless, there is some advice against placing files in the 'shadowrun_core' folder, whereof I am unaware). bytes files into shadowrun_core\data\portraits\ <- create this folder if it doesn't exist move the portrait pictures into shadowrun_core\art\portraits\ Option B - place the custom files into 'shadowrun_core' subfolders The 'seattle\data\portraits' folder should have at least these files: move the portrait pictures into seattle\art\portraits\ Option A - place the custom files into 'seattle' subfolders bytes files, which are the ones the game recognizes.ħ) Open up the zip file you just saved and extract these files somewhere easy to find:Ĭ:\Program Files (x86)\Steam\steamapps\common\Shadowrun Returns\Shadowrun_Data\StreamingAssets\ContentPacks and: The only use of the Editor in this guide is to actually convert the. At this point, the Editor is no longer necessary. and save the zip file somewhere easy to find. It is safe to "discard" changes when asked.Ħ) Select File -> Publish Content Pack To. This is important, otherwise the Editor won't recognize the files we just edited. Now back in the Editor, we should follow these steps:įile -> Recent Content Packs -> C:/Users/./custom_portraits Here we will only use the Editor to convert some text files into. Don't just put files in the content pack's root folder as was shown in this guide. Also, if we didn't check the "Resource Content Pack only" option when creating the new content pack, there should be a 'data' subfolder here, but such folder can be ignored.Īs a side note, if you're developing a full mod on itself, a more structured directory is probably required. No need to move the pictures around just yet, we'll get there later. Our content pack folder should have at least these items: Inside this folder, create 2 new text files with the same name chosen for the content pack: In our example it is:Ĭ:\Users\\Documents\Shadowrun Returns\ContentPacks\custom_portraits We can name it whatever we like, but for this example we're going to name it 'custom_portraits'.Ģ) Find the folder where the content pack has been created. We have our pictures set, so now let's get them to show up in game.ġ) Open up the game Editor and create a new content pack. ![]()
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Mac terminal solarized11/24/2023 ![]() In old age shortsightedness is caused by the lens loosing its elasticity and remaining squeezed, and longsightedness by it losing flexibility and the cillary muscle losing strength so that the lens cannot be squeezed as much. The lens in the eye focuses this expanding cone back into a contracting one that comes to a point on the retina corresponding to the position of the pixel "out there on the screen".įocusing is achieved by a muscle around the eye's flexible lens, the cillary muscle, which squeezes the lens into a more spherical shape to cause rays entering the eye to bend more, brings no objects closer to the eye into focus, or by the cillary muscle relaxing, allowing the lens to stretch back to a flatter shape, to bend rays less, bringing objects further away into focus. You can visualize the light from a point (say a pixel) that reaches the iris as a cone. When the iris is dilated (open) the eye allows as much light as possible into it. ![]() The iris in the eye expands or contracts to allow or restrict the amount of light entering the eye, attempting to maintain a constant luminosity on the retina so that either not too little, or not too much light falls on the cones and rods in the retina. Hi Dark Themers, in an earlier life I worked in optics, designing holographic cameras for bubble chamber physics, so I know a little about focussing systems and depth of field. There are plenty of competently written colorschemes at your disposal.A while back, Eliot Miranda posted a detailed message for dark theme users on the squeak-dev mailing list. Your Solarized terminal palette is broken: those are the default colors, not the Solarized colors.ĭon't waste your time on that crap. ![]() Hint: Terminal.app doesn't support that feature. or, if your terminal emulator and your Vim build allow it, use :help 'termguicolors' to force Vim to use "true colors".set up colors 0-15 of your terminal emulator and make sure both Solarized and Vim only use those colors,.That said, there are two hypothetical ways to make Solarized look "right" in a terminal: Contrary to what the official blurb might make you think, the Solarized palette is very poorly suited for terminal usage and the Vim colorscheme is not very well written at all so don't get too dreamy about that typical blue background. Solarized can't look "right" in a terminal emulator advertising itself as "256color-ready" because not a single color in its palette matches with any of colors 16-255 of the standard xterm palette. " map ctrl + c to automatically delimit brackets and quotes " set the runtime path to include Vundle and initialize I tried using the 256 color version also with adding the option let g:solarized_termcolors=256 and while it looked a little better it wasn't quite right and I would rather do it the native way with the solarized terminal theme + ansi colors.Īlso here is my vimrc: set nocompatible " be iMproved, required Also downloaded macvim and linked vim to macvims vimĪfter doing this I get an ugly vim with green lines and the colors are not quite right.I then added the two lines set background=dark and colorscheme solarized to my vimrc.Downloaded and moved solarized theme to vim/colors. ![]()
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Pikka indtagra11/24/2023 ![]() This section is defined to help you see who viewed your Instagram profile or stories for free of cost. Best Practice to Catch the Instagram Stalkers – Free and SecureĮxperts have given us some unbeatable ways to check who stalks my Instagram profile online. Try the mentioned useful tricks to protect your Instagram account. Who views my Instagram profile regularly ?. ![]() Does someone stalk my daily Instagram activities?.Who viewed your Instagram account online ?.The good news is that there are excellent methods that are quite useful to know: But, Instagram OFFICIALLY doesn’t allow tracking the Instagram Stalker or who views your Instagram Profile and stories. Knowing your Instagram stalker can be a great thing for you and helps you in many ways. Does something like this happen to you? If not, it is important to protect your Instagram account from Instagram Stalker or Insta Stalker. A stranger knows what you did last night through your Instagram story and the great thing that does not follow you. Such questions come to mind when you find that something non-causal happens to your Instagram account. These are some of the trending Insta queries. Instagram Stalker – What is Good and Bad ? So, beware of an Instagram Stalker who follows your Instagram profile, pictures, stories and more. They can create trouble in your life through different means. A person who stalks an Instagram account secretly (without following) is known as Instagram Stalker. Honestly, it is not possible to check who viewed your Instagram profile or account without the help of some applications. But, Here The Big Question is Can I Check Who Viewed My Instagram Profile? ![]() It also helped people promote business, share their thoughts, start a campaign, and many other things. Celebrities and elite people are connected to their fans globally through Instagram. It is especially popular for sharing images and videos for different purposes. It allows us to see the profile and stories of any member.
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Expertgps does not open11/24/2023 ![]() Now you've got a safe back-up of all of the important data on your TRX7, and use ExpertGPS to find and create new waypoints, routes, and tracks to download to your Magellan GPS. Once they've backed up the new data from their GPS, they can clear the memory again, keeping their GPS ready for their next trip.īackup your Magellan TRX7 waypoints, routes, and tracksīackup your TRX7 waypoints, routes, and tracks by using ExpertGPS to transfer them to your laptop or desktop computer. When they get back, they use ExpertGPS to upload all of their Magellan waypoints, routes, and tracks onto their computer and save it. ![]() They can then download as much data as possible onto their GPS (leaving some room for GPS data collection out in the field). Before each outdoor adventure or visit to a project site, they use ExpertGPS to back up the contents of their GPS, and then clear the GPS data memory. Smart ExpertGPS users have figured out how to eke out every last bit of memory space on their Magellan GPS receivers. Once you reach that limit, your GPS can't hold any more data. ![]() Your Magellan TRX7 has limited storage space for waypoints, routes, and tracks. ExpertGPS even lets you upload Excel, Google Earth, CAD, and GIS data to your Magellan TRX7! Upload waypoints, routes, and tracks to your GPS and print a matching map out to take with you into the field. Transfer data back to your Magellan TRX7 with a single click. Upload new waypoints, routes, and tracks to your Magellan GPS ExpertGPS will read and write waypoints, routes, and tracks to and from this card when you click Receive from GPS or Send to GPS in ExpertGPS. Your GPS stores its data on a memory card. Uploading and Downloading Magellan TRX7 Data Download your Magellan TRX7 waypoints, routes, and tracks to your computerĮxpertGPS can transfer Magellan TRX7 waypoints, routes, and tracks. New features were added to ExpertGPS on July 7, 2023ĮxpertGPS runs on Windows 11 and Windows 10. Download Our Free ExpertGPS Trial Right Now!ĭownload now and start your free trial of ExpertGPS 8.52 We're so confident ExpertGPS will save you time (as a GPS data downloader, coordinate converter, map viewer and editor, and GIS, CAD, and GPS data converter) that we make this guarantee: if ExpertGPS doesn't pay for itself in 14 days, we'll refund your money - and you can keep the software! Magellan Data Upload and Download, Map Making, Adding Waypoints and POIs, Tracklog Tricks, Coordinate Conversion, Google Earth and KML, ArcGIS and Shapefiles, AutoCAD DXF, Backing up your Magellan data, Geotagging your Photos, Downloading updates for your Magellan TRX7ĭownload a fully-featured trial of ExpertGPS, or buy your copy today. We've collected dozens of tips and tricks designed to save you time and money when mapping with your Magellan TRX7. Thousands of businesses and GPS users depend on ExpertGPS mapping software to upload and download Magellan TRX7 waypoints, routes, and tracks, make maps of their GPS data over seamless USGS topo maps and aerial photos, and convert and transfer Magellan TRX7 data to and from Excel, Google Earth, ArcGIS, and AutoCAD. ExpertGPS Pro contains all of the professional mapping features of high-end CAD and GIS packages, but without the steep learning curve and at a fraction of the price (now only $79/yr). ExpertGPS even works with your own scanned maps, and data from over 100 different mapping, GIS, and CAD programs.ĮxpertGPS Home is an affordable outdoor trip planner at only $33/yr. ExpertGPS makes it easy to transfer waypoints, routes, and tracks, as well as GPS, GIS, and CAD data, to and from your Magellan TRX7.ĮxpertGPS gives you access to every topo map in the USA, as well as high-resolution aerial photos, so you can zoom in on any trail or job site. ![]() Download ExpertGPS! Introducing ExpertGPSĮxpertGPS is GPS map software for your Windows computer, tablet, or laptop. You're About to Unleash the Full Potential of Your Magellan TRX7!ĭon't Miss These Easy Tips to Supercharge Your GPS. ![]()
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5686 lilyview way11/23/2023 ![]() ![]() The phone number (210) 621-1612 is also used by Leticia Tanner, Ofilia Cardona, Jesse Tanner, Michael Tanner. Leticia has (210) 792-9220 (Cellco Partnership), (210) 621-1612 (Southwestern BellCellco Partnership) as phone numbers. Based on the residence history, we can come to the assumption that at least five people, including Monty Ray Venable, Christina Reyna Venable, Steve Lindley may know Leticia. Foreclosed These properties are owned by a bank or a lender who took ownership through foreclosure proceedings. These are also known as bank-owned or real estate owned (REO). They are owned by a bank or a lender who took ownership through foreclosure proceedings. Leticia has also lived in Canyon Lake, TX and Elmendorf, TX. 5686 Lilyview Way is a 2,578 square foot house on a 6,300 square foot lot with 5 bedrooms and 3.5 bathrooms. Auction Foreclosures These properties are currently listed for sale. 17545 FM306, Canyon Lake, TX 78133 is included in Leticia’s address history. Their name are David Cardona, Mary Guerrero Corona, and two others. Leticia has five email addresses you can use to get in touch with them: Shady Forest Drv, Elmendorf, TX 78112-6154 is where Leticia lives. Box 1114, San Antonio, TX 78294-1114 is the known post office box number. Leticia Tanner, Ofilia Cardona, Jesse Tanner, Michael Tanner were identified as possible owners of the phone number (210) 621-1612. There is a chance that the phone number (210) 241-8573 is shared by Juan Pena, Jesse Tanner. From the previous addresses, we can assume that Leticia might be known by around one people, this includes Arturo R Pina. Leticia has the experience of living in two different cities: San Antonio, TX and Elmendorf, TX. Leticia’s previous address is 3830 Waterwood Pass Dr, Elmendorf, TX 78112. Begin your property search by selecting an address below. Their name are David Cardona, Mary Guerrero Corona, and two others. Find people by address using reverse address lookup for 5682 Lilyview Way, Elk Grove, CA 95757. ![]() ![]() Leticia is currently living at 23107 Shady Forest Drv, Elmendorf, TX 78112-6154. Some of Leticia’s friends can call her Leticia L Cardona, Leticia Tanner, Letty Tanner, Leticia Cardona, Leticia Lynn Cardona, Leticia L Tanner, Leticia L Tainner. The listed occupation for now is Sales Occupations. ![]()
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![]() This casserole is hearty enough to be served by itself or it pairs nicely with a side salad or fresh fruit. When ready to bake, allow to thaw in the refrigerator overnight and then bake as instructed. Assemble as instructed in an aluminum pan ( do not bake) and cover tightly with aluminum foil for up to 2 months. Is cheesy cowboy tater tot casserole freezer friendly ? While I have not tested each of these options, I would imagine it would give it a similar overall taste. Healthier options: try using lite sour cream, low fat or fat-free milk, fat-free cream of mushroom soup, and reducing the cheese to 1 cup. You will want to use canned or frozen to be sure it cooks through thoroughly.Ĭheese: mild cheese tastes best such as Colby, Mozzarella, Cheddar, or Monterey Jack. Vegetables: many different vegetables such as green beans, carrots, or peas would taste great. Meat: turkey, chicken, or sausage would also taste delicious in this dish. Add the diced pickles and diced tomatoes to the pan and stir. Once the ground beef is fully cooked, drain the grease from the pan. Add the diced onions to the pan with the ground beef while it’s cooking. SECOND STEP: In a large skillet cook ground beef, onion, and garlic until beef is cooked through. Cook over medium heat until ground beef is no longer pink and onions are translucent. Using a large cast iron pan or large skillet, add ground beef, onions, garlic, seasonings and pepper. *See the recipe card at the bottom of the page for detailed instructions. Cook ground beef in a large saute pan over medium-high heat with a dab of butter or margarine. Spray a 9x13 baking dish with cooking spray. Preheat oven to 425° and lightly spray a 13 x 9 baking pan with cooking spray. Store– store leftovers in the refrigerator for 2-3 days. If the tots are on top of each other, they don’t cook evenly and won’t be able to crisp up on top.īake– uncovered at 375 degrees for 45-50 minutes or until tots are slightly browned and crispy and the center is warmed through. Mix– ground beef, corn, cream of mushroom soup, sour cream, milk, 1/2 tsp garlic powder, 1/2 tsp onion powder, pepper, and 1 cup cheese in a large bowl. It’s a really easy recipe, all you have to do is:īrown– ground beef in the skillet with 1/2 tsp garlic powder and 1/2 tsp onion powder. It’s cheesy, easy, and delicious! How to make it Plus it only involves a few simple steps so I don’t have to worry about cooking all night. It’s stick-to-your-ribs hearty that’s filled with staple ingredients like ground beef or turkey, corn, sour cream, and cream of mushroom soup. This Cheesy Cowboy Tater Tot Casserole is a feel-good comfort food recipe the whole family enjoys. I am always looking for an easy family meal that even my picky eater kids will devour. Sure to become a family favorite! Family favorite dish Cheesy Cowboy Tater Tot Casserole is an easy and delicious weeknight meal made with seasoned beef, sweet corn, and crispy tater tots. ![]()
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Log cabin interior colors11/23/2023 ![]() ![]() From bold and dark to light and bright, these are the best colors for every room in a small house, from a cramped hallway to a tiny living room, or bedroom. You will quickly learn that while white is the obvious choice, it isn't the only option. Since the experts know best, we rounded up some of our favorite designer spaces that showcase great paint color ideas for smaller homes and rooms, no matter how neutral or vibrant you lean. ![]() ![]() And while we definitely have some clever maximizing tips to help you to do so ahead, the truth is that there really is no one-size-fits-all solution-it's more about finding the right paint color for your style (and the light you get!) and then choosing a strategic layout. It's no secret a new paint job can do wonders for a space, and that's true with making it appear larger as well. But the simplest solution might be in the swatch book: Paint.
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